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Type: 
Journal
Description: 
We present a bio-inspired renal microdevice that resembles the in vivo structure of a kidney proximal tubule. For the first time, a population of tubular adult renal stem/progenitor cells (ARPCs) was embedded into a microsystem to create a bioengineered renal tubule. These cells have both multipotent differentiation abilities and an extraordinary capacity for injured renal cell regeneration. Therefore, ARPCs may be considered a promising tool for promoting regenerative processes in the kidney to treat acute and …
Publisher: 
Public Library of Science
Publication date: 
30 Jan 2014
Authors: 

Anna Giovanna Sciancalepore, Fabio Sallustio, Salvatore Girardo, Laura Gioia Passione, Andrea Camposeo, Elisa Mele, Mirella Di Lorenzo, Vincenzo Costantino, Francesco Paolo Schena, Dario Pisignano

Biblio References: 
Volume: 9 Issue: 1 Pages: e87496
Origin: 
PLoS One