In the last years, many studies have been performed on metal nanoparticles because of their possible applications as chemical and biological sensors. Particularly, new design and fabrication strategy of plasmonic transductors have been proposed in order to enhance their sensing performances and reproducibility. Unfortunately, the most used fabrication methods for metallic nanostructured systems, such as EBL and FIB, are less accessible choices for scientists and industrial applications due to their critical drawbacks, like low speed and high-cost.